Descripción
Características:
Protector absorbente de un sólo uso.
La gran dimensión del núcleo, le confiere grandes propiedades de absorción y protección.
La estructura romboidal de su superficie absorbente forma unos canales de difusión de la orina de forma que es distribuida a lo largo de estos canales sin producirse encharcamientos.
El interior de los rombos, gracias a la cantidad de celulosa que llevan, es capaz de absorber rápida y efectivamente la orina que les llega a través de esos canales.
La elevada compactación de la celulosa y el calandrado en forma de rombos, forma una estructura compacta que le confiere elevada resistencia a la rotura ante los tirones y casi nulas posibilidades de desmoronamiento de la celulosa.
La capa externa del protector está decorada con figuras de color, que confieren al producto un cuidado aspecto higiénico y permiten diferenciarle de la ropa de cama, facilitando el trabajo diario del cuidador.
Absorbe las emisiones de orina que pudieran escaparse de cualquier otro sistema absorbente que llevara puesto el paciente.
Aísla la piel del paciente de la humedad, manteniéndolo en perfectas condiciones de higiene.
Reduce las tareas de cambio de ropa mojada, reduciendo, igualmente, el gasto en lavandería por los escapes de orina.
Usos:
Sanitario.
Indicaciones:
En todo tipo de incontinencias, como coadyuvante de cualquier otro protector absorbente que llevara puesto el paciente.
En pacientes sondados para mantenerlos secos y limpios.
Composición:
Non-woven, constituido por fibras de polipropileno, hipoalérgico e hidrófilo en contacto con la piel, que facilita la absorción y se mantiene siempre seco.
Pasta de celulosa, blanqueada con oxígeno, libre de clorinas.
Polietileno, de color blanco con figuras de color, tratado electrónicamente en ambas caras para disminuir la electricidad estática por rozamiento. Con superficie antideslizante,
Cumple las normas:
Capacidad de absorción total ISO: 950-1.100 ml.
Según Norma ISO 11948-1 (1996): Urine-absorbing aids Part 1.
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Sermorelin, CJC-1295, and Ipamorelin are three of the most frequently discussed peptides in the field of growth hormone therapy. Although they all aim to stimulate the body’s natural production of growth hormone (GH), each has distinct characteristics regarding potency, duration of action, receptor affinity, and clinical applications. Understanding these differences is essential for anyone considering GH peptide therapy, whether for anti-aging purposes, athletic performance enhancement, or medical conditions such as growth hormone deficiency. Sermorelin vs. CJC-1295 vs. Ipamorelin: Comparing Popular Growth Hormone Peptides Sermorelin Origin: A synthetic analogue of the naturally occurring growth hormone-releasing hormone (GHRH). Structure: Short 8-amino-acid peptide that mimics the first eight residues of GHRH. Mechanism: Binds to GHRH receptors in the pituitary, prompting endogenous GH release. Duration: Effects are relatively short; typical dosing schedules involve daily injections with peak GH levels occurring within a few hours post-injection. Clinical use: Approved for diagnosing growth hormone deficiency in children and adults; also used off-label for anti-aging and body composition improvements. CJC-1295 (with DAC) Origin: A modified GHRH analogue designed to increase half-life by attaching a drug affinity component (DAC). Structure: Longer peptide (21 amino acids) that resists enzymatic degradation. Mechanism: Activates the same GHRH receptor but with prolonged activity due to its resistance to proteases and binding to albumin via the DAC. Duration: Sustained GH release for up to 24–48 hours, allowing once-daily or even twice-weekly dosing in some protocols. Clinical use: Used for chronic GH stimulation, particularly in research settings where continuous elevation of IGF-1 is desired. Ipamorelin Origin: A selective ghrelin receptor agonist (growth hormone secretagogue). Structure: Short 5-amino-acid peptide with high specificity for the growth hormone secretagogue receptor (GHSR). Mechanism: Mimics the natural hunger hormone ghrelin, stimulating GH release without significant appetite changes. Duration: Rapid onset and short duration; typically administered twice daily to maintain steady GH levels. Clinical use: Popular among bodybuilders and athletes for its mild side-effect profile and ability to increase lean muscle mass while minimizing water retention. Key Comparative Points Feature Sermorelin CJC-1295 (with DAC) Ipamorelin Receptor target GHRH receptor GHRH receptor GHSR (ghrelin receptor) Half-life ~30–60 min 24–48 h ~2–3 h Dosing frequency Daily Daily or twice weekly Twice daily Appetite effect Minimal None None Water retention Rare Possible Rare Side-effect profile Mild injection site pain Mild Very mild What Are GH Peptides and How Do They Work? Growth hormone peptides are short chains of amino acids engineered to interact with the pituitary gland or hypothalamus, thereby modulating the secretion of endogenous growth hormone. Unlike exogenous recombinant human growth hormone injections, which deliver a fixed dose directly into circulation, GH peptides stimulate the body’s own regulatory systems. 1. Hypothalamic–Pituitary Axis Overview The hypothalamus releases two key hormones: growth hormone-releasing hormone (GHRH) and somatostatin. GHRH stimulates the pituitary to release GH; somatostatin inhibits it. GH, in turn, acts on peripheral tissues, stimulating the liver to produce insulin-like growth factor 1 (IGF-1), which mediates many of the anabolic effects. 2. Peptide Interaction with Receptors GHRH analogues (Sermorelin, CJC-1295) bind directly to GHRH receptors on pituitary somatotrophs, mimicking natural stimulation. GHSR agonists (Ipamorelin, Sermorelin if mis-categorized) bind to the ghrelin receptor, another pathway that also triggers GH release. 3. Signal Transduction Pathways Receptor binding activates intracellular cascades such as phospholipase C, calcium influx, and protein kinase pathways. These cascades culminate in the exocytosis of GH from pituitary cells into the bloodstream. 4. Resulting Physiological Effects Elevated IGF-1: The primary mediator of growth, muscle hypertrophy, and metabolic regulation. Improved Body Composition: Increased lean mass, reduced visceral fat, enhanced recovery. Cardiovascular Benefits: Potential improvements in endothelial function and lipid profiles. Neuroprotective Effects: Emerging evidence suggests cognitive benefits with sustained GH stimulation. 5. Advantages of Peptide Therapy Over Direct GH Injection Endogenous Regulation: The body can modulate GH secretion based on physiological needs, reducing the risk of supraphysiologic levels that may lead to insulin resistance or edema. Reduced Side-Effect Profile: Lower incidence of joint pain before and after dianabol fluid retention compared to high-dose GH injections. Flexibility in Dosing: Ability to tailor dosing schedules (daily vs. weekly) based on peptide pharmacokinetics. 6. Common Administration Practices Subcutaneous injection is the standard route, typically using a 1 mL syringe with a fine needle. Dosage ranges vary: Sermorelin often 0.2–0.5 mg daily; CJC-1295 may be 100–200 µg once or twice weekly; Ipamorelin is usually 100–250 µg twice daily. Some protocols combine peptides to leverage synergistic effects (e.g., Sermorelin with Ipamorelin). 7. Monitoring and Safety Regular blood tests for IGF-1, GH levels, thyroid function, and lipid panels are recommended. Watch for signs of hypoglycemia, edema, or joint discomfort. Long-term safety data is limited; most evidence comes from short-to-medium term studies. In summary, while all three peptides aim to boost natural growth hormone production, their mechanisms, pharmacokinetics, and clinical applications differ markedly. Sermorelin offers a straightforward GHRH mimic with a brief action window; CJC-1295 provides sustained stimulation through a longer half-life; Ipamorelin delivers rapid GH release via the ghrelin pathway with minimal side effects. Understanding these nuances allows practitioners and patients to select the most appropriate peptide for their specific goals, whether they involve medical treatment of hormone deficiencies or enhancement of physiological performance.
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Some data about the development of clitoromegaly can be found from analysis in female-to-male transsexual patients. In one study, stretched clitoral length elevated from 1.4 cm at baseline to 3 cm after four months of receiving 200 mg testosterone cypionate each different week (226). Related results have been noticed in a study administering 1.000 mg testosterone undecanoate every 3 months (227). If the dosages are exceeded, some oral steroids may cause harm to the liver. Some people consider that they’re secure for men and women, while others suppose that they are solely secure for men. The truth is that anabolic steroids may be secure for each men and women, however there are some issues that you want to hold in mind before utilizing them. Additionally, through the consumption of anabolic steroids, catabolic processes lower, and restoration after exercise improves. Completely all physical qualities change for the higher, that is what is important in sports. Salts of alpha-ketoglutaric acid (magnesium, potassium and calcium) enhances the ability of muscles to accumulate glutamine in sufferers with acute catabolism even stronger than that used for the same purpose leucine. Alpha-ketoglutarate participates within the Krebs cycle (fatty acid utilization mechanism) and provides the carbon skeleton of glutamine molecule. Some AASs only have medicinal makes use of, such as testosterone undecanoate (Nebido). Oxymetholone (Anadrol) is an instance of a steroid with both medicinal and efficiency makes use of. It’s widespread for athletes who exercise for long amounts of time to make use of a lab-made sort of erythropoietin called epoetin. Androstenedione, also known as andro, is a hormone everybody’s physique makes. The body turns andro into the hormone testosterone and a form of the hormone estrogen. Anavar (Oxandrolone) holds a special place on the earth of anabolic steroids for its suitability and relatively delicate nature for feminine customers. It has gained recognition amongst girls seeking performance enhancement, body recomposition, or athletic enchancment. Anavar’s low androgenic properties make it much less likely to cause virilization, a set of masculinizing side effects. This characteristic is particularly appealing for feminine athletes who need to avoid the event of masculine features similar to deepening of the voice, excessive hair growth, or clitoral enlargement. Oxandrolone is renowned for its capacity to contribute to varied health objectives, together with muscle definition, strength enchancment, enhanced endurance, and fat loss. This table provides a comparability of Anavar’s results on these key features, giving you an outline of the potential advantages it presents. Please notice that individual results could range, and it is essential to make use of Anavar responsibly and under professional steerage. Wherever you want so as long as it’s carried out inside the scope of the regulation, and the regulation could additionally be so open it doesn’t exist or it might be so tight you’ll need a prescription that won’t provide you a lot at all. Enhances muscle mass, endurance, and fats loss with fewer unwanted aspect effects. Steroids could be legally obtained in Canada with a sound prescription. Medical Doctors prescribe them for conditions such as testosterone deficiency, delayed puberty, and muscle loss as a end result of persistent sicknesses. Consulting a healthcare provider is important earlier than considering steroid use. As such, it remains to be seen whether or not they present efficacy within the case of AAS-induced hypogonadism, as PCT is often performed for a few weeks. In the HAARLEM study, testosterone ranges had been similar three months after cessation of AAS use in those that did and didn’t perform PCT, but a small helpful impact within this time-frame could not be excluded (46). Finally, hCG immediately stimulates the testes to produce testosterone by binding to the luteinizing hormone/choriogonadotropin receptor (LHCGR) which it shares with LH. This might result in continued suppression of LH and FSH levels when employed as PCT, but is assumed by AAS customers to assist in restoration of testicular function. This may be probable in choose circumstances which demonstrate biochemical evidence of major hypogonadism (elevated gonadotropin levels with low testosterone levels), but evidence is missing. There isn’t any good-quality proof indicating that AAS use is damaging to the kidneys. Anabolic steroid prices range broadly relying on the precise medication being bought and how it is being accessed. Anabolic steroids for sale on the black market additionally are inclined to see significant worth fluctuations primarily based on provide and demand at any given moment. As with different side effects, some AAS users self-medicate to mitigate this unfavorable shift in lipid profile. The actual anabolic steroid black market that existed presently was fairly miniscule, and the majority of these seeking to buy and use anabolic steroids would accomplish that via medical doctors, pharmacies, and medical professionals. Up till the late Eighties, anabolic steroids have been prescribed drugs and medicine, very comparable to another, which was available only by way of the prescription of a licensed physician. However, no management or legal guidelines over anabolic steroids existed, and the sources previously mentioned as were largely unregulated. 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