De acuerdo con la legislación vigente, Botiquin Sans aceptará la devolución de productos, por cualquier causa o razón amparada en la ley vigente, en un plazo máximo de 14 días naturales desde la recepción de la mercancía por parte del cliente. Vencidos estos 14 días no será posible aceptar la devolución.
Para ello se deben cumplir las condiciones mínimas exigibles legalmente y expuestas en esta web y que se detallan a continuación;
Tal y como establece la LEY 47/2002, de 19 de diciembre, de reforma de la Ley 7/1996, de 15 de enero, de Ordenación del Comercio Minorista, NO SE ACEPTARÁN en ningún caso devoluciones de los siguientes tipos de productos:
- Contratos de suministro de bienes cuyo precio esté sujeto a fluctuaciones de coeficientes del mercado financiero que el vendedor no pueda controlar.
- Contratos de suministro de bienes confeccionados conforme a las especificaciones del consumidor o claramente personalizados, o que, por su naturaleza, no puedan ser devueltos o puedan deteriorarse o caducar con rapidez.
- Contratos de suministro de grabaciones sonoras o de vídeo, de discos y de programas informáticos que hubiesen sido desprecintados por el consumidor, así como de ficheros informáticos, suministrados por vía electrónica, susceptibles de ser descargados o reproducidos con carácter inmediato para su uso permanente.
- Contratos de suministro de prensa diaria, publicaciones periódicas y revistas.
CONDICIONES GENERALES DE DEVOLUCIÓN: - El plazo de devoluciones establecido por Botiquin Sans es de 14 días naturales desde el momento de la recepción del pedido por parte del cliente. Transcurrido este plazo no será posible aceptar la devolución.
- El cliente tendrá la opción de poder devolver todo el pedido o parte de este, siempre y cuando se cumplan las condiciones de devolución establecidas por Botiquin Sans.
- El cliente podrá iniciar la solicitud de devolución enviando un correo electrónico a devoluciones@botiquinsans.com para poder gestionar con nosotros el trámite.
- Los gastos de envío en caso de devolución voluntaria correrán a cargo del cliente. En los casos en que la devolución sea originada por alguna incidencia ajena al comprador, los gastos de envío serán asumidos por la empresa.
- El producto deberá ser devuelto en su embalaje original con todos los accesorios que contenga en perfecto estado y protegido, evitando pegatinas, precintos o cintas adhesivas adosadas directamente sobre la superficie o embalaje primitivo del artículo, en su embalaje original, sin abrir. En caso contrario la empresa se reserva el derecho de rechazar la devolución.
- Nuestro departamento de calidad comprobará a la recepción del producto, su estado. En el caso de que se detecte que el producto ha sido abierto o manipulado, será motivo suficiente para denegar la devolución al cliente.
En este caso el cliente tendrá la opción de recoger el producto en nuestras instalaciones en un plazo de 10 días naturales. Siempre que el producto recibido no sea apto para la devolución, porque no se recibe en buenas condiciones o es un producto no sujeto a devolución. El cliente dispondrá de un plazo de 10 días naturales para recoger dicho producto en nuestras instalaciones, pasados estos 10 días la empresa tendrá derecho a destruirlo. - Una vez recibido el producto para realizar la devolución, y realizadas las comprobaciones pertinentes por parte de nuestro control de calidad, que determinaran si la devolución es apta, se procederá al abono de esta, utilizando para ello la misma vía de pago por la que se recibió el ingreso, en un plazo no superior a 30 días.
- En función de la normativa vigente (Real Decreto Legislativo 1/2007, Texto Refundido de la Ley General para la Defensa de los Consumidores y Usuarios) no se aceptan devoluciones de productos de alimentación como leches infantiles, papillas, complementos alimenticios, etc.., puesto que no es posible asegurar el control de calidad de dichos artículos.
Además, debido a cuestiones de higiene, no se aceptan devoluciones de fajas, bragas, sujetadores, pañales, gafas, muñequeras, rodilleras, juguetes sexuales, ni ningún otro accesorio íntimo o cualquier otro artículo de similares características. Tampoco se aceptarán devoluciones de mascarillas, entre otros.
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It could additionally be argued that by at present’s requirements this in vivo method, which was developed over 50 years in the past, is unsophisticated given the large developments in molecular biology since that time. Regardless Of the criticism that this strategy has attracted, it’s of notice that anabolic steroids with high myotrophic exercise and beneficial index values, for instance, nandrolone (esterified), oxymetholone, methandienone and stanozolol are nonetheless out there as medicines in many nations. These steroids stay fascinating as a doping agent to boost sporting performance (as evident by the statistics collated by WADA) and for bodybuilding functions. As an adjunct, a lot of the physiological importance of non-genomic actions of androgens continues to be to be elucidated, not least with respect to androgen-induced cell-cycle development. The induction of second messenger signal transduction cascades by steroids commonly occurs within seconds to a few minutes, in contrast to genomic exercise of the basic steroid receptors that takes 30–60 min. The complexity of those mechanisms is described in detail elsewhere (Cato et al., 2002; Heinlein and Chang, 2002a; Losel et al., 2003). In The End, gene transcription could additionally be modulated by these ‘non-genomic’ pathways however a well-recognized exception is the rapid elevation of calcium ion inflow by a pathway that is confined to the cytoplasm. This may probably outcome in the early onset of situations generally observed in long-term customers, corresponding to dyslipidaemia, hypertension, erectile dysfunction, and cognitive impairment [3, 44, 45]. Relating To the shortage of expertise with energy coaching, a untimely use of anabolic steroids may improve the danger of injuries on tendons and muscle ligaments suddenly required to assist the workload of drug-enhanced muscular tissues [46,47,48]. The most serious complication of anabolic steroid use is the development of hepatic tumors, either adenoma or hepatocellular carcinoma. The hepatic tumors arise in patients on long term androgenic steroids, often throughout remedy of aplastic anemia or hypogonadism, but often in athletes or physique builders utilizing anabolic steroids illicitly. Tumors are usually discovered after 5 to 15 years of use, however onset inside 2 years of starting remedy with testosterone esters has been described. Many of the case reviews have occurred in sufferers with other danger elements for cancer, such as Fanconi’s syndrome, iron overload or persistent hepatitis C (from blood transfusions). Changes in life circumstances and opposed well being circumstances were described as widespread triggers for changes in behaviour, together with the cessation of anabolic steroid use. Prevalence of AAS use is higher amongst teams with specific traits similar to professions the place measurement or energy is an asset [206–209], amongst gay and bisexual men [20, 22, 29, 210, 211] and people using or who’ve beforehand used different medicine [212] [30, 33, sixty seven, 212–214]. The Place a patient is receiving remedy, there might be a variety of things that affect the appropriateness of delivering any type of AAS intervention or investigating any other potential harms. For example, in lots of the research identified, the individuals treated had discontinued their AAS use a substantial time previous to seeking remedy. Of course, some AAS customers within the population are well over age 45 – particularly males who competed in bodybuilding competitions or Olympic events in the Nineteen Sixties and 70s, such as the Swedish sample described above (Lindqvist et al., 2007). However our experience from interviews of numerous older weightlifters, along with printed reviews within the media, suggests that the doses of AAS used in the 1960s and 70s have been sometimes a lot lower than these used right now. It should also be remembered that the majority AAS users prior to 1980 have been competitive athletes, presumably making an attempt to optimize their well being and efficiency, and infrequently utilizing other illicit drugs for leisure purposes. For example, among the older athletes in the Swedish sample, more than 80% reported that they had never used any leisure illicit medication of their lives. By comparability, most modern AAS users aren’t competitive athletes, and many use giant quantities of other illicit leisure medicine (Kanayama et al., 2003b) and different probably hazardous body-image drugs (Kanayama et al., 2001b; Parkinson and Evans, 2006). Thus with advancing age, the outcomes of those people could additionally be fairly totally different from the outcomes of older elite athletes. Important signs, including heart rate and blood strain, and fundamental chemistries, corresponding to sodium, potassium, hemoglobin, hematocrit, BUN (blood urea nitrogen), creatinine, hepatic, and lipid profiles, must be monitored fastidiously. Monitoring these parameters will assist the clinician to determine drug choice, remedy dose, and period, and will help to alert the prescriber to probably critical opposed effects that necessitate the discontinuation of therapy. Abuse of anabolic steroids, nevertheless, may end up in significant harm to the physique. In humans, abuse can result in coronary heart illness, sexual and reproductive disorders, immunodeficiencies, liver injury, stunted growth, aggressive behaviour, susceptibility to connective tissue harm, and (in females) irreversible masculinization. It is attention-grabbing that after coaching the mature ranges of miR-1, miR-206 and miR-133 lower both at the tissue level and the plasma level (Kirby et al., 2015). Furthermore, miR-206 plasma ranges have been reported to be up-regulated in aged human skeletal muscle (Kim et al., 2014). This article offers a systematic evaluate and meta-analysis on the role of miRNAs as potential new molecular biomarker of AAS use/abuse. Notably, this paper analyzed the “miRNA signature” use as biomarkers for health problems, focusing on the organ damages which are associated to ASS use/abuse. Moreover, this evaluate goals to offer a future prospect for much less invasive or non-invasive procedures for the detection of circulating miRNA biomarkers as doping assumption signaling. Upon additional inquiry, he had a prior hemoglobin A1C of 6.9% within the recent previous which was by no means followed upon. What was shocking about this result, was the analysis of diabetes mellitus despite his low-body fats ranges and very high ranges of bodily exercise throughout his life. Lipid panel returned significant for low-density lipoprotein (LDL) degree of 168 mg/dl, high-density lipoprotein (HDL) stage of 52 mg/dl, and triglyceride level of seventy eight mg/dl. The conclusion derived from the evidence presented is that AAS publicity throughout adolescence, a important interval of brain organization, alters the normal pattern of mind development in addition to neurotransmitter perform and grownup conduct patterns. In each people and animal models, AAS exposure induces adjustments in neural structure and neurotransmitter operate. This suggests an influence of AAS on mind reworking throughout this important interval that may have long lasting effects on habits. Moreover, one other study demonstrated that supraphysiological doses of AASs impair the helpful effects of bodily exercise on hippocampal cell proliferation and apoptotic signaling [41]. Endurance train improves the redox system stability by stabilizing the mitochondrial membrane, leading to a reduction of apoptotic results of ND in neural cells [25]. Flowchart of constructive and negative effects of anabolic-androgenic steroid (AAS) administration. Prolonged and excessive doses of testosterone and his derivatives result in severe consequences in all body tissues and organs. Antagonistic effects are quite common in steroid users, with some affecting over 10% of customers. It was additionally demonstrated that androgenic potency and metabolic resistance are positively linked to the diploma of liver injury [82]. The presence of apoptosis in brain areas of rats handled with long-term administration of nandrolone was instructed in a latest study. In this regard, a hyperlink between oxidative stress and NF-Kb signaling was described, promoting mind injury in particular areas, such because the hippocampus, striatum and frontal cortex [32]. Furthermore, it was discovered that every day injections of stanozol in male grownup rats for 28 days led to histopathologic adjustments in the hippocampus by activating apoptotic and pre-apoptotic cells [40]. References: PedsElite